Humalog (insulin lispro) should be stored in a refrigerator (36° to 46°F [2° to 8°C]) until it is opened, but do not freeze it. You can store your Humalog in the refrigerator until the expiration date if it has not been opened.

How long is lispro unrefrigerated?

An exam review for pharmacists lists the expiration date for opened vials of Humalog as 4 weeks, but other vials of human insulin are listed as 30 days unrefrigerated and 3 months refrigerated. Cartridges of R and Lispro are listed as stable for 4 weeks and 70/30 or N for 1 week (5).

How long can Humalog stay unrefrigerated?

In-use Humalog KwikPen should be stored at room temperature, below 86°F (30°C) and must be used within 28 days or be discarded, even if it still contains Humalog.