2,3-BPG binds with high affinity to Hemoglobin, causing a conformational change that results in the release of oxygen. Local tissues can then pick up the free oxygen. This is also important in the placenta, where fetal and maternal blood come within such close proximity.

What does Bisphosphoglycerate Mutase do?

Bisphosphoglycerate mutase (EC 5.4. 2.4) (BPGM)' is a trifunctional enzyme whose main function is to synthesize 2,3-diphosphoglycerate (2,3-DPG), the most abundant or- ganic form of soluble phosphate in the red cells in man and many other mammalian species.

What does a mutase enzyme do?

A mutase is an enzyme of the isomerase class that catalyzes the movement of a functional group from one position to another within the same molecule. In other words, mutases catalyze intramolecular group transfers.