In nondiabetics, beta-blockers represent minimal risk of affecting glucose control. In insulin-dependent diabetics, beta-blockers can prolong, enhance, or alter the symptoms of hypoglycemia, while hyperglycemia appears to be the major risk in noninsulin-dependent diabetics.

Do beta-blockers raise or lower blood sugar?

2. Beta-Blockers for Conditions Such as Arrhythmia and Anxiety. This large class of drugs is used to lower blood pressure and treat a variety of other conditions, including irregular heartbeat and anxiety, but they can also raise your blood sugar levels.

Why do beta-blockers cause hypoglycemia?

β-blockers

The mechanism responsible for β-blocker–induced hypoglycemia involves inhibition of hepatic glucose production, which is promoted by sympathetic nervous stimulation. In addition, adrenergic counterregulation is diminished, resulting in a reduction in glycogenolysis.