Despite that, however, Hit won't be able to defeat Jiren in a fight. As explained by Vados during the Tournament of Power, Jiren's powers are even beyond time, which means no matter how much Hit improves his time-skip, he is more likely to lose the fight than not.

Who can kill Jiren?

2 Can Defeat: Goku

But without Ultra Instinct, Jiren still has the advantage over Goku. In order to defeat Jiren, Goku had to team up with both Frieza and Android 17. On his own, the only hope Goku has of defeating Jiren is by fully mastering Ultra Instinct, and being able to activate it at will.

Can Jiren be defeated?

Dragon Ball Super finished its anime series with the big Tournament of Power battle between Goku and Jiren, and in an unexpected turn, Goku actually lost the fight, and needed the teamwork of old foes (Freeza and Android 17) in order to finally beat Jiren, and bring home the win for Universe 7.