DNA replication occurs during the S phase (the
When and where does replication occur?
Replication occurs in the nucleus during the S phase of the cell cycle in eukaryotes, and replication occurs continuously in prokaryotes.
What causes DNA replication to occur?
The initiation of DNA replication occurs in two steps. First, a so-called initiator protein unwinds a short stretch of the DNA double helix. Then, a protein known as helicase attaches to and breaks apart the hydrogen bonds between the bases on the DNA strands, thereby pulling apart the two strands.