Degassing is a crucial step after mixing (sometimes degassing is also required after casting) to eliminate residual pores in the slurry. These pores can be introduced during either mixing or the chemical reaction, or they can form as a result of entrapped air during casting.

What is the purpose of degassing?

Degassing or degasification is a method for removing dissolved gases from liquids. It plays an essential role in applications where the presence of gases in a liquid would be detrimental, such as mobile phases for HPLC and numerous organic reactions.

Why is degassing important in HPLC?

Online degassing is important when doing HPLC, FPLC, GPC, and uHPLC because degassing will remove dissolved gas therefore avoiding bubble formation. ... Low pressure mixing: systems are more prone to bubble formation. The solvents used for the mobile phase are mixed before the pump.