A Mind Without Limits: This ending involves knocking out — but not killing — all of the typhons in and around Talos 1. It preserves the station, the research and knowledge contained therein and anyone left alive. This is (arguably) the good ending. ... Talos 1 is destroyed along with the typhons, research and neuromods.

Which Prey ending is better?

A Mind Without Limits would be considered the "good" ending of Prey, but there's also an option to kill Alex during this playthrough which alters the final scene. This Prey ending involves the classic option of blowing up the Talos 1 and all the research into the Typhon it holds.

How do you get the best ending in Prey?

To earn the best possible ending, you'll need to earn “Empathy” — empathy is the morality system of Prey. The system is completely invisible, but you'll only get the 'best' ending if you've earned a high empathy score.