Triptans are a family of tryptamine-based drugs used as abortive medication in the treatment of migraines and cluster headaches. This drug class was first introduced in the 1990s. While effective at treating individual headaches, they do not provide preventive treatment and are not considered a cure.

What does a triptan do?

Triptan drugs work like a brain chemical called serotonin. This helps quiet down overactive pain nerves. In other words, triptans reverse the changes in your brain that caused your migraine.

Do triptans make you sleepy?

The tablets usually work within 30 to 60 minutes. The spray and injection work quicker. Common side effects include feeling or being sick, feeling sleepy or dizzy. Do not take migraine medicines such as ergotamine or other triptans when taking sumatriptan.