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What Is Aav Serotype?

Marcus Vance • • 6 min read
What Is Aav Serotype?

AAV Serotypes
These serotypes differ in their tropism, or the types of cells they infect, making AAV a very useful system for preferentially transducing specific cell types. The chart below gives a summary of the tropism of AAV serotypes, indicating the optimal serotype(s) for transduction of a given organ.

Why is AAV used in gene therapy?

AAV, or adeno-associated virus, is currently the main viral vector that researchers use and further develop for gene therapy because it is considered to be non-pathogenic to humans and because it has been successfully altered to prevent its integration into the genome, thus eliminating DNA damage and unpredictable ...

Is AAV BSL 2?

Generally, AAV is classified as a Biosafety Level 1 (BSL-1) organism, unless a helper virus is used, then it would be classified as Biosafety Level 2 (BSL-2).

Marcus Vance
Author

Marcus Vance

Marcus Vance is a cybersecurity auditor and technology writer dedicated to educating the public about online safety, data privacy regulations, enterprise security, and emerging cyber threats.