In most experimental and clinical studies,^99-102 giving nonsteroidal anti-inflammatory drugs resulted in decreased nausea and vomiting and improved gastrointestinal transit. Many clinicians use laxatives as a treatment for paralytic postoperative ileus.

Can you give laxatives with ileus?

Patients with post-operative ileus, opioid-induced constipation, or a soft stool will benefit from a stimulant laxative, such as senna or picosulphate. *In resistant cases, additional therapy can be given via manual evacuation.

What is the best treatment for ileus?

Neostigmine. Neostigmine, an acetylcholinesterase inhibitor, has been used for the treatment of ileus because of its ability to facilitate the activity of acetylcholine and induce GI contractions, especially in the colon.