Subendothelial matrix molecules are found in the extracellular space and on the surface of cells in the intima and consist of proteoglycans, collagen, elastin, fibronectin, vitronectin, fibulin, and a variety of bone-related matrix molecules.

What does Subendothelial mean?

Medical Definition of subendothelial

: situated under an endothelium subendothelial tissues.

What is the endothelium?

The endothelium is a thin membrane that lines the inside of the heart and blood vessels. Endothelial cells release substances that control vascular relaxation and contraction as well as enzymes that control blood clotting, immune function and platelet (a colorless substance in the blood) adhesion.