You use by and large to indicate that a statement is mostly but not completely true. By and large, it went well.

How do you use the word by and large?

when everything about a situation is considered together: There are a few things that I don't like about my job, but by and large it's very enjoyable.

Is by in large correct?

by and ˈlarge

(informal) used when you are saying something that is generally, but not completely, true: By and large, I enjoyed my time at school.