Glycans attached to matrix molecules, such as proteoglycans, are important for the maintenance of tissue structure, porosity, and integrity. ... The external location of glycans on most glycoproteins can provide a general shield, protecting the underlying polypeptide from recognition by proteases or antibodies.

What is the glycans function?

Glycans have many protective, stabilizing, organizational, and barrier functions. The glycocalyx that covers all eukaryotic cells and the polysaccharide coats of various prokaryotes represent a substantial physical barrier.

What makes the study of glycans unique?

Glycans have diverse biological functions that are distinct from those of nucleic acids and proteins. ... Glycans with catalytic activity are extremely rare [4]. Nevertheless, glycans do have critical roles in the maintenance of cell or tissue structure, molecular signal transduction, and cell recognition.