Thiazide diuretics can cause hypercalcemia while
loop diuretics
Loop diuretics are diuretics that act at the ascending limb of the loop of Henle in the kidney. They are primarily used in medicine to treat hypertension and edema often due to congestive heart failure or chronic kidney disease.
› wiki › Loop_diuretic
Can diuretics cause low calcium?
Thiazide diuretics block the thiazide-sensitive NaCl transporter in the distal convoluted tubule, and can decrease calcium excretion.
Why do diuretics cause hypercalcemia?
By increasing calcium reabsorption from the luminal membrane into the interstitium in exchange for sodium, thiazides reduce urine calcium levels and increase blood calcium.
