Fick's first law
J is the diffusion flux, of which the dimension is amount of substance per unit area per unit time. J measures the amount of substance that will flow through a unit area during a unit time interval.
What factors affect diffusive flux?
The greater the difference in concentration, the quicker the rate of diffusion. The higher the temperature, the more kinetic energy the particles will have, so they will move and mix more quickly. The greater the surface area, the faster the rate of diffusion.
What increases diffusion flux?
Increasing the concentration gradient also increases the diffusive flux into the tissue. This can be accomplished by decreasing the interstitial fluid concentration or keeping the capillary concentration high by increasing the flow in the capillary.
