Despite potential side effects, Wellbutrin can provide several benefits to people who take it, including: treatment of major depressive disorder and seasonal affective disorder. helping people stop smoking. less sexual side effects, such as lowered sex drive, than other antidepressants.

Does Wellbutrin work immediately?

Sleep, energy, or appetite may show some improvement within the first 1-2 weeks. Improvement in these physical symptoms can be an important early signal that the medication is working. Depressed mood and lack of interest in actiities may need up to 6-8 weeks to fully improve.

How long does it take for Wellbutrin to kick in?

When used as a treatment for depression, Wellbutrin (buproprion) usually takes around six to eight weeks before it starts fully working as a treatment for depression. However, you may begin to experience improvements in your sleep habits, appetite and energy levels as early as one to two weeks of treatment.