If the suppository comes out after you insert it, you may not have pushed it far enough into the rectum. Be sure to push the suppository past the sphincter, which is the muscular opening of the rectum.

How long does it take for a suppository to dissolve?

On average most suppositories will melt in 10-15 minutes, although it can take up to a half hours. If you are still having trouble contact your doctor or pharmacist for more information. Question: How long after inserting the vaginal suppository should I wait to have sex?

Is it normal for a suppository to come out?

Suppositories are usually safe. Yet there can be some problems when you take medicine this way: Some of the medicine might leak back out. Sometimes your body doesn't absorb the drug as well as if you took it by mouth.