Clinical trials indicate that the efficacy of primaquine is higher than 95% as terminal prophylaxis at doses of 30 mg daily for 14 days (in combination with a blood schizonticide such as chloroquine) and greater than 85% as prophylaxis [86].

Does prophylaxis prevent malaria?

Although minor differences in expert opinion exist between jurisdictions (i.e. United States, Europe and Canada), experts do agree that chemoprophylaxis is an essential component of malaria prevention in areas of high transmission.

How long can you take malaria prophylaxis?

Prophylaxis should begin 1–2 weeks before travel to malarious areas. It should be continued by taking the drug once a week, on the same day of the week, during travel in malarious areas and for 4 weeks after a traveler leaves these areas (see Table 4-10 for recommended dosages).