Conclusion: In fetuses with abnormal karyotype, the second nuchal translucency measurement tends to be increased or unchanged, while in normal cases the size of nuchal translucency is generally reduced.

Does nuchal translucency decrease with gestational age?

Results: Nuchal translucency measurements varied considerably with gestational age; this variation followed a fetus-specific pattern. In 94% of cases, we observed an increase followed by a steady decrease in nuchal translucency measurement.

Can a thick nuchal translucency be normal?

Many healthy babies have thick nuchal folds. However, there is a higher chance for Down syndrome or other chromosome conditions when the nuchal fold is thick. There may also be a higher chance for rare genetic conditions.