Early on in the process Windows will copy all the files it needs from the USB drive to your hard drive. Typically when the first reboot starts, you can remove it. In the unlikely event that the installation process needs it again, it will ask for it.

When should I remove bootable USB?

6 Answers. While booted from the USB drive, it should not be removed. (There is an exception: if you use the the boot option toram , and there is no persistence on the USB drive, the system data from the USB drive is copied to the RAM, and the USB drive can be unmounted and removed).

Can I reuse USB after installing Windows 10?

Yes, we can use the same Windows installation DVD/USB to install Windows on your PC provided it is a retail disc or if the installation image is downloaded from Microsoft website.