No, System Restore will not have any effect on BIOS settings.

What happens when system is restored using System Restore?

System Restore is a Microsoft® Windows® tool designed to protect and repair the computer software. … It repairs the Windows environment by reverting back to the files and settings that were saved in the restore point. Note: It does not affect your personal data files on the computer.

Is System Restore the same as factory reset?

Resetting your PC and doing a system restore can both be effective methods to alter your PC to either factory settings or to a previous point in PC usage. Resetting your PC takes it back to factory settings. … A system restore will take your PC to a previous period in time.