How do I create a bootable USB drive for Linux Mint?

In Linux Mint

Right-click the ISO file and select Make Bootable USB Stick, or launch Menu ‣ Accessories ‣ USB Image Writer. Select your USB device and click Write.

Can I run Linux Mint on a USB stick?

As has already been noted, It is relatively easy to run a “Live session” of Mint – or other Linux distros – from a USB stick. It is also possible to install Mint on a USB stick provided it is large enough – in exactly the same way as it would be installed on an external hard drive.