Signs and symptoms from pharyngitis caused by group C and G streptococci may be indistinguishable from GAS infection. The need for treatment in these cases is unclear because they have not been associated with the development of acute rheumatic fever.

Does strep C need to be treated?

Non–group A beta-hemolytic streptococci (groups C and G) also can cause acute pharyngitis; these strains are usually treated with antibiotics, although good clinical trials are lacking. Fusobacterium necrophorum causes endemic acute pharyngitis, peritonsillar abscess, and persistent sore throat.

What is Group C strep throat?

Group C streptococci (GCS) are livestock pathogens and they often cause zoonotic diseases in humans. They are Gram-positive, in mostly β-hemolytic and facultative anaerobes.