Phenazines serve as electron shuttles to alternate terminal acceptors, modify cellular redox states, act as cell signals that regulate patterns of gene expression, contribute to biofilm formation and architecture, and enhance bacterial survival.

Is phenazine an antibiotic?

Phenazine antibiotic inspired discovery of potent bromophenazine antibacterial agents against Staphylococcus aureus and Staphylococcus epidermidis. Org Biomol Chem.

What bacteria is phenazine active against?

Phenazine-1-carboxylic acid, synthesized by fluorescent pseudomonads, is effective against various fungal and bacterial pathogens such as Gaeumannomyces graminis var. tritici, Pythium sp., Polyporus sp., Rhizoctonia solani, Actinomyces viscosus, Bacillus subtilis, and Erwinia amylovora [51].