The wizards would have some magical tricks that would help to even the playing field, but muggles are very good at killing. Ultimately, the wizards wouldn't stand a chance.
Can a muggle beat a wizard?
It is certainly true that wizards have power and ability beyond your average muggle. Yet, if wizards could be killed by non-wizards, it is not too much of a stretch to suggest that a muggle could injure or even kill a wizard themselves.
Did muggles kill wizards?
The author's explanation for this is simple: at some point, near the end of the Middle Ages, there was a war between wizards and muggles, and muggles somehow managed to not only defeat the Wizarding World but kill their most powerful wizards – thus why there were no more truly powerful wizards left (even though Albus ...