The method of standard addition is a type of quantitative analysis approach often used in analytical chemistry whereby the standard is added directly to the aliquots of analyzed sample.

Why is standard addition method used?

The method of standard addition is a quantitative analysis technique used to minimize matrix effects that interfere with analyte measurement signals. Unknown component concentrations are often elucidated through a range of analytical techniques, such as light spectroscopy, mass spectrometry, and electrochemistry.

What does standard addition mean?

'Standard additions' is a generally applicable calibration technique, devised to overcome a particular type of matrix effect that would otherwise give rise to a biased result. This 'rotational effect' is manifested as a change in the slope of the calibration function.