Yes, once you check them in and they go off on the conveyor belt, your baggage will be screened by an X-Ray machine and also often with chemical sniffers. If there is any doubt or something suspicious about your bag, a member of security personnel will inspect it by hand.
Do they XRAY your luggage at the airport?
U.S. Department of Homeland Security (DHS), Transportation Security Administration (TSA) The TSA uses x-ray machines to screen carry-on items and checked luggage.
Is Checked baggage Xrayed?
Baggage Screening: In airports, luggage is scanned using x-ray scanners. Carry-on luggage passes through x-ray scanners at the security checkpoint, while checked baggage passes through x-ray or CT (Computed Tomography) scanners in secured areas of the airport.