Nevertheless, Izzie came back in Grey's Anatomy Season 6 Episode 12. The character revealed she was cancer free. ... In the end, Izzie left Seattle and divorced Alex. A decade after Heigl's last episode as Izzie, Grey's Anatomy Season 16 confirmed the character got back together with Alex.

What episode does Izzie come back?

Nevertheless, Izzie came back in the 12th episode of season 6, where she revealed that she was cancer-free and asked Alex to come back in her life.

Is Izzie coming back in season 17?

Season 17 will be the first season of Grey's Anatomy without Justin Chambers as Dr. ... Karev was revealed to have been reunited with ex-partner Izzie Stevens (Katherine Heigl, making a surprise return to Grey's).