The physical and functional separation of the inner cell mass from the
Is inner cell mass pluripotent?
The inner cell mass (ICM) forms within the blastocyst, prior to its implantation within the uterus. ... The ICM is the only pluripotent cell lineage in the blastocyst. The ICM forms the epiblast and hypoblast layers, which develop into to the embryonic tissues and extraembryonic tissues, respectively.
What does the inner cell mass become?
The inner cell mass differentiates into a bilaminar embryo, consisting of an epiblast (presumptive embryonic ectoderm, mesoderm, and endoderm, as well as some extraembryonic ectoderm and mesoderm) and a hypoblast (presumptive yolk sac endoderm and extraembryonic mesoderm).