Proband: The family member through whom a family's medical history comes to attention. The proband may also be called the index case, propositus (if male), or proposita (if female). ...

Who is the proband in a pedigree?

​Proband. A proband is an individual being studied or reported on. A proband is usually the first affected individual in a family who brings a genetic disorder to the attention of the medical community.

What does Propositus mean?

Propositus: The initial subject presenting a mental or physical disorder, who causes a study of his or her heredity in order to determine if other members of the family have had the same disease or carry it. Also called index case and proband.