These tumors most commonly present with abdominal pain, bleeding or signs of intestinal obstruction. They spread most commonly to sites within the abdominal cavity and to the liver, although there are rare cases of spread to the lungs and bone.

Where are leiomyosarcoma found?

Leiomyosarcoma, or LMS, is a type of rare cancer that grows in the smooth muscles. The smooth muscles are in the hollow organs of the body, including the intestines, stomach, bladder, and blood vessels. In females, there is also smooth muscle in the uterus.

Where does leiomyosarcoma spread to first?

Leiomyosarcoma most often begins in the abdomen or uterus. It starts as a growth of abnormal cells and often grows quickly to invade and destroy normal body tissue.