The disease starts in the bone marrow. Bone marrow creates red and white blood cells, platelets and antibodies that protect the body against infection. After the antibodies have done their work, the body breaks them down. When the bone marrow cells produce antibodies that cannot be broken down, amyloidosis develops.

Who gets amyloidosis most commonly?

Age. Most people diagnosed with amyloidosis are between ages 60 and 70, although earlier onset occurs. Sex. Amyloidosis occurs more commonly in men.

Where does amyloidosis come from?

Causes. In general, amyloidosis is caused by the buildup of an abnormal protein called amyloid. Amyloid is produced in your bone marrow and can be deposited in any tissue or organ. The specific cause of your condition depends on the type of amyloidosis you have.