ESTRUMATE^® (cloprostenol injection) is a leading prostaglandin and improves reproductive performance in dairy and beef cattle. This reproductive tool allows for better management of heat detection, breeding, calving intervals and the scheduling of entry of heifers into the milking herd.

What does Estrumate do for horses?

Estrumate is a synthetic prostaglandin drug (cloprostenol) used to “short cycle” mares to bring them back into season (“heat”) more quickly. It does this by causing destruction of the corpus luteum, a progesterone-secreting structure that forms in the area on the ovary where there was ovulation.

Does Estrumate abort calves?

Since ESTRUMATE results in an abortion rate of approximately 95% in cattle up to 4 1/2 months of gestation and causes some cattle in later pregnancy to abort, it should not be given to pregnant animal unless induced abortion is desired.