Spleno- is a combining form used like a prefix representing the word spleen, an organ in the abdomen that helps regulate blood and is part of the immune system. It is often used in medical terms, especially in anatomy and pathology. Spleno- comes from the Greek splḗn, meaning “spleen.”

What is Splen o medical term?

Medical Definition of splenohepatomegaly

: abnormal enlargement of the spleen and the liver.

What does the word splenomegaly break down to mean?

pathology. abnormal enlargement of the spleen. Word origin. C20: from Greek splēno-, from splēn spleen + megalo-, from megas large + -y3.