(d) Pleomorphic calcifications can either be benign or malignant.

Are pleomorphic calcifications cancerous?

The morphology of microcalcifications can be pleomorphic (varying shape, size, and density), rounded, punctuate, or amorphous. Pleomorphic calcifications are potentially alarming as they can be cancerous in nature.

What are pleomorphic calcifications?

Calcifications with fat necrosis can happen as a result of surgery or radiation to the chest area. Microcalcifications that vary in size and shape are of more concern — you may hear these referred to as “pleomorphic calcifications” — and they may be clustered in a specific area of the breast.