Home » Solar Destinations Hub » Where Is Arginase Found?

Where Is Arginase Found?

Chloe Bennett • • 6 min read
Where Is Arginase Found?

In most mammals, two isozymes of this enzyme exist; the first, Arginase I, functions in the urea cycle

urea cycle
The urea cycle (also known as the ornithine cycle) is a cycle of biochemical reactions that produces urea (NH2)2CO from ammonia (NH3). This cycle occurs in ureotelic organisms. The urea cycle converts highly toxic ammonia to urea for excretion.
› wiki › Urea_cycle
, and is located primarily in the cytoplasm of the liver. The second isozyme, Arginase II, has been implicated in the regulation of the arginine/ornithine concentrations in the cell.

How is arginase produced?

Arginase-Ornithine Pathway. ... Polyamines are produced through activity of ornithine decarboxylase (ODC), followed by spermidine and spermine synthases. Polyamines also can be generated from agmatine by activity of arginine decarboxylase (ADC).

What group of enzymes does arginase belong to?

Arginase belong to the ureohydrolase family of enzymes. Arginase catalyzes the fifth and final step in the urea cycle, a series of biochemical reactions in mammals during which the body disposes of harmful ammonia. Specifically, arginase converts L-arginine into L-ornithine and urea.

Chloe Bennett
Author

Chloe Bennett

Chloe Bennett explores the intersection of pop culture, streaming entertainment, digital trends, and contemporary lifestyle. Her weekly commentary reaches thousands of culture enthusiasts.