Cramps are caused by the hormone-like lipids called prostaglandins that make your uterus contract to help get rid of its lining. Prostaglandins are also involved in the inflammation and pain responses. They reside in the uterine lining and are also released from this lining.

Why do cramps cause pain?

During your menstrual period, your uterus contracts to help expel its lining. Hormonelike substances (prostaglandins) involved in pain and inflammation trigger the uterine muscle contractions. Higher levels of prostaglandins are associated with more-severe menstrual cramps.

How do you stop cramps from hurting?