Transdermal nitroglycerin comes as a patch to apply to the skin. It is usually applied once a day, worn for 12 to 14 hours, and then removed.

Why do you take nitro patch off at night?

Since continuous 24-hour plasma concentrations of nitroglycerin do not appear to be desirable, alternative approaches to therapy are needed. A simple method to minimise tolerance with transdermal nitroglycerin patches is to remove the patch at bedtime and reapply a new patch in the morning.

How does nitroglycerin transdermal patches work?

It works by relaxing the blood vessels and increasing the supply of blood and oxygen to the heart while reducing its work load. When used regularly on a long-term basis, this helps prevent angina attacks from occurring. This product is available in the following dosage forms: Patch, Extended Release.