Chlorothiazide is used to treat edema (fluid retention; excess fluid held in body tissues) caused by various medical problems, including heart, kidney, and liver disease and to treat edema caused by using certain medications including estrogen and corticosteroids.

What are the benefits of Diuril?

Chlorothiazide is a "water pill" (diuretic) that causes you to make more urine. This helps your body get rid of extra salt and water. This medication is also used to decrease swelling (edema) caused by conditions such as cancer, congestive heart failure, liver disease, and kidney disease.

What is the difference between hydrochlorothiazide and chlorothiazide?

HCTZ has one additional hydrogen substituted on a nitrogen on the sulfonamide ring compared with chlorothiazide. All thiazides have a similar dual-ring structure.