Adenosarcoma is a mixed form of uterine sarcoma characterized by the presence of benign glandular epithelium mixed with a sarcomatous stroma. Histologically broad papillary structures, clefts, glands, and cystic structures are lined by endometrial-type epithelium with minor areas of focal cytologic atypia (Fig.

What is an adenosarcoma?

A tumor that is a mixture of an adenoma (a tumor that starts in the gland-like cells of epithelial tissue) and a sarcoma (a tumor that starts in bone, cartilage, fat, muscle, blood vessels, or other connective or supportive tissue). An example of an adenosarcoma is Wilms tumor.

Is adenosarcoma cancerous?

Summary. Uterine adenosarcoma is a rare malignancy. It is defined as a biphasic tumor composed of both sarcomatous stroma and benign epithelium. While the sarcomatous component usually is a low-grade homologous uterine sarcoma, the epithelium most often consists of endometrium-like cells.