Thrombin is used to prevent and stop bleeding whenever oozing blood and minor bleeding from microvessels is accessible. Thrombin is available under the following different brand names: Recothrom,
What is the purpose of thrombin?
Thrombin is an unique molecule that functions both as a procoagulant and anticoagulant. In its procoagulant role it activates platelets through its receptor on the platelets. It regulates its own generation by activating coagulation factors V, VIII and even XI resulting in a burst of thrombin formation.
Why is thrombin used in surgery?
There are many ways thrombin is used during a surgical procedure to effect hemostasis. It can be used alone, in combination with an absorbable hemostatic carrier, or in a manufactured combination with fibrin.
