If the player character kills Trish and her three bodyguards, Nelson will run away from the scene and can still be found alive in the Colonial Taphouse should he not be harmed. ... Days after being killed his father will confront the player character about the death of his son. The Sole Survivor can admit to it or lie.
What happens if Henry Cooke dies?
After getting the mission from Paul Pembroke, if the Sole Survivor gets into the Colonial Taphouse before Nelson Latimer, Henry Cooke will shoot at them. If Cooke dies before he is convinced to stop seeing Darcy, she will continue to go to the Colonial Taphouse, whether or not there is anyone there to serve her.
Should you pay Marowski?
Once there, he'll give you a week to pay 2000 caps as compensation for stealing his chem shipment. Refusing to pay makes him and the rest of Goodneighbor hostile. Paying will leave him on good terms.