Memory integrity is one feature of core isolation which regularly verifies the integrity of the code running those core processes in an attempt to prevent any attacks from altering them. We recommend that you leave this setting on, if your system supports it."

Is it good to turn on memory integrity?

Memory integrity is a feature of core isolation. By turning on the Memory integrity setting, you can help prevent malicious code from accessing high-security processes in the event of an attack.

Is it safe to turn off memory integrity?

Microsoft said early on that Memory Integrity might cause compatibility problems, and even silently switches it off when it gets in the way of boot-critical drivers.