Abiraterone acetate works by inhibiting specific “enzymes” in your adrenal glands that are responsible for making androgens. For this reason, there is an increased risk of over production of mineralcorticosteroids in your body while on abiraterone acetate.

What is the mechanism of action of abiraterone?

Mechanism of Action

Abiraterone acetate is converted in vivo to abiraterone, an androgen biosynthesis inhibitor, that inhibits 17 a-hydroxylase/C17,20-lyase (CYP17). This enzyme is expressed in testicular, adrenal, and prostatic tumor tissues and is required for androgen biosynthesis.

Does abiraterone acetate cure prostate cancer?

Abiraterone won't cure your prostate cancer, but it can help keep it under control and has been shown to help some men live longer. It can also help to treat or delay symptoms, such as pain and tiredness.