Posted Jun 22, 2020. In many cases, denaturation is reversible. Since the primary structure of protein is intact, once the denaturing influence is removed, proteins can regain their native state by folding back to the original conformation. This process is called renaturation.

How is denaturation reversed?

Reversing Denaturation

Once the denaturing agent is removed, the original interactions between amino acids return the protein to its original conformation and it can resume its function. However, denaturation can be irreversible in extreme situations, like frying an egg.

Is denaturation is reversible?

In many cases, denaturation is reversible (the proteins can regain their native state when the denaturing influence is removed). This process can be called renaturation. ... Denaturation can also be irreversible.