Rough ER lies immediately adjacent to the cell nucleus, and its membrane is continuous with the outer membrane of the nuclear envelope. The ribosomes on rough ER specialize in the synthesis of proteins that possess a signal sequence that directs them specifically to the ER for processing.

Where is ER rough found?

Rough ER lies immediately adjacent to the cell nucleus, and its membrane is continuous with the outer membrane of the nuclear envelope. The ribosomes on rough ER specialize in the synthesis of proteins that possess a signal sequence that directs them specifically to the ER for processing.

When was rough ER found?

Discovery of Endoplasmic Reticulum (ER):

It was discovered independently by Porter (1945) and Thompson (1945). The name was given by Porter in 1953.