Protein acetylation is one of the major post-translational modifications (PTMs) in eukaryotes, in which the acetyl group from acetyl coenzyme A (Ac-CoA) is transferred to a specific site on a polypeptide chain.
What are 3 types of post-translational modifications?
Types of post-translational modification
- Phosphorylation.
- Acetylation.
- Hydroxylation.
- Methylation.
How is histone acetylation post-translational modification?
Histone post-translational modifications are covalent modifications of histones by phosphorylation on serine or threonine residues, methylation on lysine or arginine, acetylation and deacetylation of lysines, ubiquitylation of lysines and sumoylation of lysines.