Based on the properties of dobutamine and milrinone, medication administration and respective venous access may play a role in medication selection as dobutamine generally must be given via central line (e.g., peripherally inserted central catheter, tunneled line, and port) where as milrinone may be given via a ...

Does milrinone require a central line?

Adult Critical Care Protocol: May be administered by IV infusion by a nurse in Adult Critical Care. Each loading dose and infusion rate must be ordered by physician; nurses are not approved to titrate milrinone. Must be administered via central venous access device.

How do you give milrinone infusion?

Adults: Milrinone Injection should be given as a loading dose of 50μg/kg administered over a period of 10 minutes usually followed by a continuous infusion at a dosage titrated between 0.375μg/kg/min and 0.75μg/kg/min according to haemodynamic and clinical response, but should not exceed 1.13mg/kg/day total dose.