Seneca is a city in Oconee County, South Carolina, United States. The population was 8,102 at the 2010 census.

What county is Seneca South Carolina?

The largest city in Oconee County, Seneca is situated in the northwestern corner of South Carolina in the foothills of the Blue Ridge Mountains.

Is Seneca SC a nice place to live?

Seneca is the most desirable area in South Carolina and one of the best in the nation if you're a retiree looking for a tax-friendly city with amenities much sought after by seniors.