Beta Cross Laps measures C-terminal telopeptide of mature Type 1 collagen and has been proposed as a reliable specific marker for bone resorption. The levels are elevated with increased bone resorption in patients. ... The patient needs to fast prior to testing.

What does high Crosslaps mean?

Elevated levels of beta-C-terminal telopeptide (CTx) indicate increased bone resorption. Increased levels are associated with osteoporosis, osteopenia, Paget disease, hyperthyroidism, and hyperparathyroidism.

What does high P1NP mean?

When bone tissue is renewed, small fragments of the new collagen are found in the bloodstream, including P1NP. The higher the P1NP level in the blood, the more bone formation is taking place. P1NP levels rise within a few weeks when osteoporosis is being treated successfully with teriparatide.